San Diego Chargers at Indianapolis Colts 2010 NFL Predictions, Odds, and Picks Week 12:  Head football coach Norv Turner will lead his San Diego Chargers on the road to Lucas Oil Stadium to take on quarterback Payton Manning and his Indianapolis Colts on NBC’s Football Night in America at 8:20 PM ET Sunday.  The Chargers are gaining momentum at 5-5 in 2nd place in the AFC West after a traditionally slow start while the Colts are 6-4 2nd in the AFC South and are looking to stay perfect at home this season.  The Chargers have won the last three against the Colts holding them to no more than 24 points.  “They are a team that creates problems for you just in terms of matchups,” head football coach Jim Caldwell told the Colts’ official website. “It’s been a real battle with them throughout the years as well.”  According to Coach Turner it’s about their scheme.  “I think that the 3-4 defense helps us defensively. I think that we’ve done a good job giving them a lot of different looks so we’ve been able to get pressure,” he said. “And then we’ve been able to score points and keep the ball and that’s a big part of playing good defense.”  The odds makers at Bodog have the Indianapolis Colts -2 1/2 point favorites at home against the San Diego Chargers.

The Colts are coming off a 31-28 loss to the New England Patriots where Manning threw a late interception while Indy was driving and in field goal range moving then to 6-4 ATS for the season.  Quarterback Payton Manning completed 38 of 52 passes for 396 yards and 4 touchdowns but had 3 picks the last one costing them the game.  San Diego is 4-1 SU in its last 5 games when playing Indianapolis.  Vegas odds makers have the Indianapolis Colts as +1200 odds to win the 2011 Super Bowl.

San Diego has won 3 in a row including its last contest 35-14 at home against the Denver Broncos moving them to 5-5 ATS for the season.  Quarterback Phillip Rivers completed 15 of 24 passes for 233 yards with 4 touchdowns and a pick hitting Patrick Crayton 3 times for 105 yards and a score.  The total has gone UNDER in 4 of San Diego’s last 5 games when playing Indianapolis.  Vegas odds makers have the over/under for the total score at 50 1/2 points combined of the San Diego Chargers and Indianapolis Colts.

I predict a Colts win at home.